10th International Symposium on Poisonous Plants
Program and Abstracts

Chairpersons: Dr. Daniel Cook and Dr. Jim Pfister 2018, St. George, Utah, USA
Past Chairpersons: Dr. Mengli Zhao 2013, ISOPP9, Hohhot, China
  Dr. Franklin Riet-Correa 2009, ISOPP8, João Pessoa, Brazil
  Dr. Kip Panter and Dr. Jim Pfister 2005, ISOPP7, Logan, Utah, USA
  Dr. Tom Acamovic 2001, ISOPP6, Glasgow, Scotland, UK
  Dr. Tam Garland 1997, ISOPP5, San Angelo, Texas, USA
  Dr. Steven Colegate and Dr. Peter Dorling 1993, ISOPP4, Fremantle, Australia
  Dr. Lynn James 1989, ISOPP3, Logan, Utah, USA
  Dr. Alan Seawright and Dr. Ross McKenzie 1984, Joint U.S./Australian Symposium, Brisbane, Australia
  Dr. Alan Seawright, Dr. Selwyn Everest, and Dr. Lynn James 1977, Joint U.S./Australian Symposium on Poisonous Plants, Logan, Utah, USA
Sunday, September 16, 2018
6:00 to 8:00 pm
Reception and Registration
Red Lion Hotel, 850 S. Bluff St., St. George, Utah
Hotel Reception Phone: (435) 628-4235
Monday, September 17
7:30-8:20am Registration
8:20-8:30am Welcome and Opening Ceremony
Dr. Daniel Cook, Acting Research Leader, PPRL, Logan
SESSION 1 – Global Perspectives on Poisonous Plants Session Chair: Dr. Tam Garland
8:30-9:00 Invited Lecture: Safety of botanical dietary supplements Joseph Betz
9:00-9:20 Induction of resistance in cattle to poisoning by monofluoroacetate from plants using non-toxic salt Benito Soto-Blanco
9:20-9:40 Non-toxicological factors affecting cattle responses to poisonous plants Ben Green
9:40-10:00 EURL for mycotoxins & plant toxins in food and feed Monique de Nijs
10:00-10:15 BREAK
10:15-10:35 Ferulenol exposure of calves in Corsica (France) Gilbert Gault
10:35-10:55 Ergot as a potential emerging disease in Pacific Northwest, USA A. Morrie Craig
10:55-11:15 Photosensitization diseases of animals: classification and a weight-of-evidence approach to primary causes Mark Collett
11:15-11:35 Restoration of rangelands degraded with annual grasses that also contain poisonous plants Clint Stonecipher
11:35-11:45 Introduction of new online journal: Poisonous Plant Research, hosted by Utah State University Kevin Welch, Associate Editor
11:45-1:00 LUNCH (On your own)
SESSION 2 – Natural Toxins & the Systems They Affect Session Chair: Dr. Dale Gardner
1:00-1:20 A functional metabolomics analysis of lolitrem B and its biosynthetic intermediates in murine brain Jane C. Quinn
1:20-1:40 'Go Slow' myopathy in dogs: a secondary plant toxicity? Hayley Hunt
1:40-2:00 Diterpene acids in Gutierrizia sarothrea and G. micorocephala and implications for cattle abortions Dale Gardner
2:00-2:20 The ophthalmic lesions of locoweed poisoning in livestock, wildlife, and rodents. Bryan Stegelmeier
2:20-2:40 Pyrrolizidine alkaloids – natural toxins risk in Queensland honey Natasha Hungerford
2:40-2:55 BREAK
2:55-3:15 Potential toxicity of pomegranates to cattle Elizabeth Read
3:15-3:35 Toxicity and anticancer activity of aloperine derived from Sophora alopecuroides L. Mingning Qiu
3:35-3:55 Eupatorium adenophorum induces Toxicological Effect on Mice Liver by Activating Pyroptosis via GSDMD/IL-1? pathway Yanchun Hu
3:55:-5:00 pm POSTER SESSION #1 Advances in Research (13)
Poster presenters to stand by their posters
A novel analytical method for simultaneous quantification of the carcinogens Ptaquiloside, Caudatoside and Ptesculentoside Vaidotas Kisielius
The disaster and toxicant mechanisms and prevention and control of locoweed in Western China Baoyu Zhao
The progress of distribution, harm and exploitation of Ligularia in northwestern Sichuan pastoral area Yanchun Hu
Swainsonine in select North and South American Astragalus species Daniel Cook
The study of metabolites from fermentation culture of Undifilum oxytropis Hao Lu
Cytotoxicity of Terminalia ferdinandiana extracts in intestinal and hepatic cancer cell lines Saleha Akter
Earwax: innovative method to detect fluoroacetate intoxication in cattle Paulo Cunha
Grazing of larkspur by susceptible and resistant Angus cattle Jim Pfister
Herbicide control of death camas Clint Stonecipher
Hazard cause, distribution, damage and control of poisonous weeds in natural grassland of China Baoyu Zhao
Idiopathic enzootic calcinosis in a goat herd in New Zealand Mark Collett
Ptaquiloside and pterosin B levels in four Brazilian ferns Benito Soto-Blanco
Liquid chromatography coupled to quadrupole time-of-flight mass spectrometry assay for quantification of protodioscin Benito Soto-Blanco
5:15 pm DINNER (on your own)
7:00 pm Dutch oven desserts and ice cream. Tonaquint Park, 1851 South Dixie Drive, St. George, UT
Tuesday, September 18
SESSION 3 – Emerging Poisonous Plant Problems and Diagnostics Session Chair: Dr. Patricia Talcott
8:00-8:20 The clinical and histologic changes of Salvia reflexa intoxication in cattle, goats and mice Bryan Stegelmeier
8:20-8:40 Diterpenoids from Salvia reflexa associated with hepatotoxicity in cattle Dale Gardner
8:40-9:00 Endophyte infected perennial ryegrass (Lolium perenne) effects on pregnant camels Linda Blythe
9:00-9:20 First giant fennel (Ferula sp.) intoxication in continental France Denis Grancher
9:20-9:40 Mass mortality of eastern grey kangaroos associated with Panicum gilvum related hepatogenous photosensitisation Jane C. Quinn
9:40-10:00 BREAK
10:00-10:20 Accumulation and depletion of the toxic amino acid indospicine in calves fed Indigofera spicata Mary Fletcher
10:20-10:40 Risk assessment of indospicine residues in bovine muscle and liver from north-west Australia Gabriele Netzel
10:40-11:00 ProMED-Mail and toxic plants Tam Garland
POSTER SESSION #2: Emerging Poisonous Plant Problems and Diagnostics (13)
11:00-12:00 Poster presenters to stand by their posters
North American hard yellow liver disease: an old problem readdressed Bryan Stegelmeier
Effect-based screening of water leachable compounds of invasive plants employing in vitro bioassays Bettina Gro Soerensen
Pyrrolizidine alkaloids in blue heliotrope (Heliotropium amplexicaule) in Australia Natasha Hungerford
Hypoglycin A exposure of horses with atypical myopathy Gilbert Gault
Relative accumulation of indospicine and its deamino-metabolites in camels fed Indigofera spicata Gabriele Netzel
Spontaneous photosensitization by Brachiaria ruziziensis in sheep Benito Soto-Blanco
Spontaneous poisoning by Taxus cuspidata in a dog Benito Soto-Blanco
Toxic effects of saponins from Cestrum axillare leaves in goats Benito Soto-Blanco
Characterisation and bioactivity of secondary metabolites of Amaranthus retroflexus L. implicated in livestock poisoning Jane C. Quinn
Regulation of swainsonine production and gene expression in fungal symbionts Ramanujam Nadathur
Acute neurological signs and deaths in rams associated with horse chestnut (Aesculus indica) ingestion Kathleen Parton
Clinical aspects of the experimental poisoning in cattle by the pods of Stryphnodendron obovatum Paulo Cunha
Cardiac changes of cattle experimentally poisoned by Palicourea marcgravii and prevented with acetamide Fabricio dos Santos
12:00 noon-1:15 pm LUNCH (on your own)
SESSION 4 – Diagnostics Session Chair: Dr. Barry Pittman
1:15-1:45 Invited Lecture: Arizona Livestock Incident Response Team (ALIRT) Peter Mundschenk
1:45-2:05 Diagnosis of dehydropyrrolizidine alkaloid (DHPA) poisoning Bryan Stegelmeier
2:05-2:25 The search for biomarkers of facial eczema following a sporidesmin challenge in dairy cows Zoe Matthews
2:25-2:45 Photosensitization and Brassica Mark Collett
2:45-3:05 Evaluation of noninvasive specimens to determine livestock exposure to teratogenic Lupine spp. Stephen Lee
3:05-3:30 BREAK
SESSION 5 – Continued - Diagnostics Session Chair: Dr. Barry Pittman
3:30-3:50 Towards understanding the aetiology of acute bovine liver disease in Australia Elizabeth Read
3:50-4:10 Diagnosis of Selenium poisoning in livestock Zane Davis
4:10-4:30 Development of a PCR-based method for detection of Delphinium species in poisoned cattle Daniel Cook
6:30 pm ISOPP banquet for all registered attendees and companions. Red Lion Hotel
Note: ISOPP Awards ceremony at the Banquet
Wednesday, September 19
7:15 am Tour (load buses) Lunch and Snacks provided. Return at 4 pm to St. George.
Bring light jacket in case of inclement weather. Lunch will be Jimmy John's sandwiches. Please fill out the order form. Lettuce wraps are available instead of bread upon request. Drinks will be provided.
Thursday September 20
SESSION 6 – Continued ADVANCES IN RESEARCH Session Chair: Dr. Ben Green
8:30-8:50 Ipomoea asarifolia and Ipomoea muelleri: investigation of tremorgenic indole diterpenes Stephen Lee
8:50-9:10 Oral toxicity of progoitrin-derived nitriles in rats and rabbits Zoe Matthews
9:10-9:30 Quantitation of Phalaris alkaloids throughout a growing season in Victoria, Australia Elizabeth Read
9:30-9:50 Is tremetone really the toxin in white snakeroot and rayless goldenrod that is responsible for causing milk sickness? Zane Davis
9:50-10:10 Asphodel exposure of sheep in Algeria Gilbert Gault
10:10-10:25 BREAK
10:25-10:45 Metabolic profiling of cytotoxic steroidal saponins in five Australian Panicum species Yuchi Chen
10:45-11:05 Identification of novel photocytotoxic plant secondary metabolites in the pasture legume Biserrula pelecinus L. Jane C. Quinn
11:05-11:25 The effect of drying temperature on the tremorgenicity of Ipomoea asarifolia in mice Kevin Welch
11:25-11:45 Nitrate accumulation in livestock fodders: a prospective aspect of nitrate poisoning in dairy animals Muhammad Avais
11:45 am-12:00 noon ISOPP10 proposals. Future of ISOPP given declining attendance? Open discussion in business meeting. Moderated by Daniel Cook
12:00 noon Closing Ceremony- Adjourn ISOPP 10